The show is adapted from the podcast with the same name produced by iHeartMedia. It narrates the life of Melissa Jesperson-Moore, who appeared on Dr. Oz's show. When she was 15 years old, she discovered that her father, Keith Hunter Jesperson, was a notorious serial killer referred to as the "Happy Face Killer." As Melissa got older, she decided to change her name to keep this dark secret hidden and completely cut off all connections with her father, who is currently serving a life sentence.